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Last updateWed, 13 Dec 2017 8pm

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Process Instrumentation in Oil and Gas

Process Instrumentation in Oil and Gas

Process instrumentation is an integral p...

Check Valves in LNG Cryogenic Service

Check Valves in LNG Cryogenic Service

Because natural gas is currently conside...

Will Smart Machines Obsolete Human Resources?

Will Smart Machines Obsolete Human Resources?

Is artificial intelligence (AI) going to...

Is Valve Live Loading an Option?

Is Valve Live Loading an Option?

Valves leak. There’s no getting ar...

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Construction and Mining: Is 2018 The Year for Growth?

Construction and Mining: Is 2018 The Year for Growth?

Tuesday, 12 December 2017  |  Kate Kunkel

While there is a degree of optimism in the mining industry that hasn’t been seen for some years, much uncertainty still exists in this sector. A...

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Industry Headlines

Emerson to Modernize Controls for Phoenix-Area Hydro Fleet

12 HOURS AGO

Arizona-based Salt River Project (SRP), one of the nation’s largest public power utilities, has selected Emerson to modernize the controls of multiple hydropower units and its central service center. SRP provides electricity to 1 million customers in the metropolitan Phoenix area and is also one...

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CIRCOR Completes Acquisition of Colfax Fluid Handling

1 DAY AGO

CIRCOR International has completed the previously announced acquisition of Fluid Handling (FH) from Colfax Corporation for approximately $693 million of cash and newly issued CIRCOR shares, and $150 million related to the assumption of pension plan liabilities linked to the FH business. FH will become...

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Chemical Industry Growth Rate Surpasses 20-Year Average

16 HOURS AGO

The U.S. chemical industry is riding a global wave of growth as the world’s major economies experience an upswing for the first time in a decade. Increased output and accelerating growth rates that surpass the previous twenty-year average will help cement the business of American chemistry as ...

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Shale Boom Leading to Record Oil Exports

17 HOURS AGO

“Americans are expected to end the year pumping oil out of the ground at rates unseen since the early 1970s. More and more of it is going overseas, giving OPEC a headache as the group restrains its own output,” Bloomberg  reports .

“Last year the U.S. tested the export waters afte...

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U.S. Manufacturing Technology Orders Up 6.3%

17 HOURS AGO

Orders for manufacturing technology kept their momentum in October 2017, gaining 6.3% over September to a total value of $428.32 million, according to the latest U.S. Manufacturing Technology Orders Report from The Association for Manufacturing Technology (AMT). Year to date, orders are up 7.6% comp...

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NAM Survey: Manufacturers’ Optimism Reaches Record High

1 DAY AGO

The National Association of Manufacturers (NAM) released the results of the Manufacturers’ Outlook Survey for the fourth quarter of 2017, showing manufacturers’ optimism has risen to unprecedented heights amid the legislative progress made on tax reform. With 94.6% of respondents saying ...

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The Biopharm Industry

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This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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