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Last updateMon, 02 May 2016 9pm

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Food and Beverage Processing

Food and Beverage Processing

When wandering the grocery store aisles,...

Variable Frequency Drives in Electric Actuators

Variable Frequency Drives in Electric Actuators

Electric actuators are vital for operati...

Braided Packing: An Old Technology with a Modern Twist

Braided Packing: An Old Technology with a Modern Twist

Compression packing is the primary metho...

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Industry Headlines

MRC Global Announces First Quarter 2016 Results

-1 DAYS AGO  |  Chris Guy

MRC Global Inc. today announced first quarter 2016 results. The company's sales were $783 million for the first quarter of 2016, which were 39% lower ...

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Industry Headlines

MRC Global Announces First Quarter 2016 Results

-1 DAYS AGO

MRC Global Inc. today announced first quarter 2016 results. The company's sales were $783 million for the first quarter of 2016, which were 39% lower than the first quarter of 2015 and 19% lower than the fourth quarter of 2015. As compared to last year, reduced customer activity across all segments ...

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CIRCOR Reports First-Quarter 2016 Financial Results

-1 DAYS AGO

CIRCOR International announced financial results for the first quarter ended April 3, 2016. In the quarter CIRCOR delivered revenue of $151 million and Adjusted EPS of $0.52.

“CIRCOR delivered solid first-quarter financial results , demonstrating ongoing progress on our margin expansion and simpl...

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Energy Sector Weighs on Construction Starts

3 DAYS AGO

At a seasonally adjusted annual rate of $660.5 billion, new construction starts in March receded 1% from February’s pace, according to Dodge Data & Analytics. Total construction starts had jumped 13% in February, led by a huge gain for the electric utility and gas plant category. The dolla...

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Chevron Investing Billions in The Permian Basin

4 DAYS AGO

At Chevron’s annual security analyst meeting last month, chairman and CEO John Watson said that his company plans on investing billions into oil & gas projects in the Permian Basin.

According to the Hobbs News-Sun , Watson predicted they could be pumping up to 350,000 barrels a day out of West ...

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ISM: Manufacturing Activity Increased in April

-1 DAYS AGO

Manufacturing expanded in April as the PMI registered 50.8%, a decrease of 1% from the March reading of 51.8%, indicating growth in manufacturing for the second consecutive month, following five consecutive months of contraction in manufacturing.

The Institute of Supply Management (ISM) reports that 15...

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House Passes Bill To Lower Import Tariffs On Manufacturers

4 DAYS AGO

This week, the House voted 415-2 for the American Manufacturing Competitiveness Act of 2016. The bipartisan, bicameral bill reforms the way Congress considers legislation for suspending tariffs on products not made in the U.S., what some are calling, “manufacturing tax breaks.” The legis...

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The Biopharm Industry

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This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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