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Last updateFri, 05 Feb 2016 4pm

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Is Your Company Ready for The New Reality?

Is Your Company Ready for The New Reality?

Since August, 2015, when VMA’s 201...

Offshore Oil Extraction and Transportation

Offshore Oil Extraction and Transportation

Offshore oil facilities come to the fore...

Back to Basics: Pressure Relief Devices, Part 2

Back to Basics: Pressure Relief Devices, Part 2

In Part 1 of Pressure Relief Devices, wh...

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Industry Headlines

U.S. Adds 151,000 Jobs, Unemployment Rate Down to 4.9%

4 HOURS AGO  |  Chris Guy

Total nonfarm payroll employment rose by 151,000 in January, and the unemployment rate dropped 0.1% to 4.9%, the lowest since Feb. 2008. Job gains occ...

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Industry Headlines

Watson Valve Announces Watson Valve Services, Australia

23 HOURS AGO

Watson Valve Services Inc. announces Watson Valve Services, Australia. Watson Valve will now have the ability to support the supply of its severe service valve products to non-U.S. domestic sites from its Australian based service agent, Process Plants International (PPi) under the name, Watson Valve...

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Velan Makes Changes to Management Team

1 DAY AGO

Velan recently announced that Executive Vice-President (EVP) Ivan Velan has decided to reduce his work scope, but will remain with the company as Special Advisor to the President, Yves Leduc. Ivan will lead key projects and continue to support the management team.

Martin Allen joined Velan’s ...

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U.S. Oil Inventories Now at Record High

1 DAY AGO

Several factors have played a part in pushing U.S. crude oil prices below $30 per barrel, including high inventory levels of crude oil, uncertainty about global economic growth, volatility in equity and non-energy commodity markets, and the potential for additional crude oil supply to enter the mark...

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FERC Approves $3.2B Sabal Trail Pipeline Project

1 DAY AGO

Sabal Trail Transmission, LLC, a joint venture of Spectra Energy Partners, LP, NextEra Energy, Inc. and Duke Energy, received a certificate of public convenience and necessity from the Federal Energy Regulatory Commission (FERC) to construct and operate the Sabal Trail interstate natural gas pipelin...

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U.S. Adds 151,000 Jobs, Unemployment Rate Down to 4.9%

4 HOURS AGO

Total nonfarm payroll employment rose by 151,000 in January, and the unemployment rate dropped 0.1% to 4.9%, the lowest since Feb. 2008. Job gains occurred in several industries, led by retail trade, food services and drinking places, health care and manufacturing. Employment declined in private edu...

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U.S. Factory Orders Down 2.9% in December

1 DAY AGO

New orders for manufactured goods in December, down four of the last five months, decreased $13.5 billion or 2.9% to $456.5 billion, the U.S. Census Bureau reported today. This followed a 0.7% November decrease. Overall, December orders were 6.6% below where they were one year ago.

Machinery orders...

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The Biopharm Industry

vmwnt12_biopharm_cvr

This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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