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Last updateFri, 24 Mar 2017 2pm

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Valve Selection in Pulp and Paper Operations

Valve Selection in Pulp and Paper Operations

Over the centuries, the pulp and paper i...

How to Improve Control Valve Performance with Positioners

How to Improve Control Valve Performance with Positioners

As the final control element in most pro...

VMA Technical Event: Engineering Valves in the Extreme

VMA Technical Event: Engineering Valves in the Extreme

While much the 2017 VMA Technical Semina...

FEL: The Preferred Phase for Valve Technical Definition

FEL: The Preferred Phase for Valve Technical Definition

A typical oil and gas capital project cy...

The Weekly Report

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Industry Headlines

Kansas City Fed Shows Manufacturing At 6-Year High

Friday, 24 March 2017  |  Chris Guy

Tenth District manufacturing activity strengthened further in March, and many indexes of expectations for future activity were at or near record highs...

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Industry Headlines

GE Oil & Gas Expands with New Sub Saharan Africa Facility

2 DAYS AGO

GE Oil & Gas opened a new facility in Takoradi Port, Ghana, expanding its global footprint and supporting local investment. The facility, which will be the primary service center for deep-water offshore projects in Ghana, has a 1,600 square meter indoor test area with capability for testing thre...

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Metso Launches Digital Program to Accelerate Growth

3 DAYS AGO

Metso has set up a Digital Program to accelerate the company’s digital capabilities, which are required to succeed in the future of minerals processing and flow control. Metso's ambition is to become one of the digital leaders in the industries it serves. This means for example turning custome...

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Shell Looking to Lower Cost of Offshore Projects

2 DAYS AGO

“With oil prices hovering around $50 a barrel or less, and a rising amount of renewable energy chipping away at market share, Shell is going lean on its deepwater projects to make sure it can eke out a profit from all of its operations,” writes ChemInfo .

For example, Shell is attempting to ...

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Report Says PA Can Support Four More Ethane Crackers

2 DAYS AGO

A new report from IHS Markit, commissioned by the state of Pennsylvania, forecasts $2.7 to 3.7 billion in investments in natural gas liquid (NGL) assets as well as the opportunity to attract additional cracker plants, and petrochemical and plastics manufacturing. IHS Markit believes the Marcellus an...

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Kansas City Fed Shows Manufacturing At 6-Year High

1 DAY AGO

Tenth District manufacturing activity strengthened further in March, and many indexes of expectations for future activity were at or near record highs. Most price indexes increased moderately. The month-over-month composite index was 20 in March , its highest reading since March 2011, up from 14 in Fe...

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Consumer Sentiment Reaches Highest Level Since 2000

5 DAYS AGO

The overall level of consumer sentiment remained quite favorable in early March due to renewed strength in current economic conditions as well as the extraordinary influence of partisanship on economic prospects. The current economic conditions component reached its highest level since 2000, largely...

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The Biopharm Industry

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This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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