06282017Wed
Last updateWed, 28 Jun 2017 5pm

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Lubricants: Always Important—Sometimes Essential

Lubricants: Always Important—Sometimes Essential

Most valve professionals take more notic...

Why Air Valves are Needed in Water Applications

Why Air Valves are Needed in Water Applications

Air valves are hydromechanical devices d...

Achieving Profitability Through Maintenance Management

Achieving Profitability Through Maintenance Management

One of the distinctions between maintena...

Control Valve Positioner Performance Diagnostics

Control Valve Positioner Performance Diagnostics

There has been discussion for some years...

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Industry Headlines

U.S. Crude, Petroleum Exports Have More than Doubled Since 2010

Wednesday, 28 June 2017  |  Chris Guy

U.S. crude oil and petroleum product gross exports have more than doubled over the past six years, increasing from 2.4 million barrels per day (b/d) i...

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Industry Headlines

Emerson in Talks to Acquire Software Company Paradigm Ltd.

1 DAY AGO

According to Bloomberg , Emerson is in talks to acquire software company Paradigm Ltd. for approximately $1.5 billion.

“Paradigm specializes in seismic data interpretation and imaging equipment to help oil and gas companies know where to drill. The logic of such a deal seems sound and will help Eme...

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VMA Members Lead MDM Top Industrial PVF Distributors List

2 DAYS AGO

Modern Distribution Management (MDM) recently published its Top Distributors list for 2017. Four of the top 5 distributors in the Industrial PVF category ; MRC Global, NOW Inc., Wolseley Industrial Group and FloWorks International; are currently VMA members.

“While oil & gas markets have start...

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U.S. Crude, Petroleum Exports Have More than Doubled Since 2010

3 HOURS AGO

U.S. crude oil and petroleum product gross exports have more than doubled over the past six years, increasing from 2.4 million barrels per day (b/d) in 2010 to 5.2 million b/d in 2016. Exports of distillate, gasoline, propane, and crude oil have all increased , but at different paces and for different...

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Mountain Valley Pipeline Gets Environmental Approval

1 DAY AGO

The Federal Energy Regulatory Commission (FERC) determined that construction and operation of the Mountain Valley Pipeline would result in some adverse environmental impacts, but the majority of these impacts would be reduced to less-than-significant levels. This determination is based on a review o...

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IMF Lowers Forecast for U.S. Growth to 2.1%

5 HOURS AGO

According to the newest forecast from the International Monetary Fund (IMF), growth in the U.S. is expected to rise 2.1% both this year and next, driven by continued solid consumption growth and a cyclical rebound in private investment. In its last forecast the IMF predicted 2.3% growth this year an...

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U.S. Durable Goods Orders Fell the Most in 18 Months

1 DAY AGO

New orders for manufactured durable goods in May decreased $2.5 billion or 1.1% to $228.2 billion, the U.S. Department of Commerce announced. This decrease, down two consecutive months, followed a 0.9% April decrease. Excluding transportation, new orders increased 0.1%. Excluding defense, new orders...

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The Biopharm Industry

vmwnt12_biopharm_cvr

This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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