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Valves in a Cement Slurry Line

Valves in a Cement Slurry Line

Basically everywhere you look in modern ...

Triple Offset Butterfly Valves

Triple Offset Butterfly Valves

Since their introduction to the market m...

Digital Valve Control Leads to Increased Plant Availability

Digital Valve Control Leads to Increased Plant Availability

Surge is characterized by fast flow reve...

Cast vs. Forged: The Ongoing Debate Takes a New Direction

Cast vs. Forged: The Ongoing Debate Takes a New Direction

In the valve industry, the cast versus f...

The Weekly Report

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Industry Headlines

Industry Headlines

VMA Members Among Plant Engineering 2016 Product of the Year Finalists

2 DAYS AGO

Several VMA members are among this year’s Plant Engineering Product of the Year finalists. Emerson has products nominated in four different categories, while Siemens has several products nominated in a total of three different categories. Chesterton and Hunt Valve have products up for awards the...

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MSS Publishes Revised American National Standard for Steel Pipeline Flanges and Receives ANSI Approval

2 DAYS AGO

The Manufacturers Standardization Society (MSS) announces that the substantially revised Standard Practice, SP-44-2016, Steel Pipeline Flanges, has been approved by the American National Standards Institute (ANSI) as a Revised American National Standard (ANS).

The first edition of MSS SP-44 was publish...

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U.S. Chemical Industry Remains Optimistic for 2017

2 DAYS AGO

Moving into 2017, the U.S. Chemical Processing Industry continues to enjoy optimism about future investment, according to Industrial Info's 2017 Global Industrial Outlook . Much of this activity stems from the continued low cost of natural gas liquids (NGLs), a primary feedstock for building-block che...

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Hydraulic Institute Celebrates Centennial with New Logo

2 DAYS AGO
Hydraulic Institute Celebrates Centennial with New Logo

The Hydraulic Institute (HI) will celebrate its centennial in 2017 with a new logo as part of a larger initiative to position HI for the next 100 years of service to the pump industry. The new logo is a key element of HI’s overall brand refresh and redesign process.

The logo includes a hidden &ld...

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U.S. Adds 178,000 Jobs, Unemployment Rate at 4.6%

1 DAY AGO

The unemployment rate declined 0.3% to 4.6% in November, and total nonfarm payroll employment increased by 178,000, the Department of Labor reported today. Employment gains occurred in professional and business services and in health care.

Employment in construction continued on its recent upward trend...

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Third Quarter GDP Revised Up to 3.2% Growth

2 DAYS AGO

Gross domestic product (GDP) in the U.S. increased at an annual rate of 3.2% in the third quarter of 2016, according to the second estimate released by the Department of Commerce. In the second quarter, real GDP increased 1.4%.

This new GDP estimate is based on more complete source data than were avail...

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The Biopharm Industry

vmwnt12_biopharm_cvr

This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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