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Wastewater Treatment

Wastewater Treatment

Society’s desire for a clean envir...

Controlling Our Water Systems, Part II

Controlling Our Water Systems, Part II

To better understand the actuators and c...

Controlling Our Water Systems

Controlling Our Water Systems

Actuators and controls are a critical pr...

Hardfacing Alloys and Processes for Advanced Ultra-Supercritical

Hardfacing Alloys and Processes for Advanced Ultra-Supercritical

Cobalt-based Stellite 6 has been the wor...

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Basics of Elastomeric Seal Design

Basics of Elastomeric Seal Design

Wednesday, 20 July 2016  |  Kate Kunkel

Engineers need critical design information when choosing a seal for a particular valve application. This includes:

  • Operating temperature and pressure r...

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Industry Headlines

Pentair Valves & Controls Rolls Out Customer Education Program

1 DAY AGO

Pentair Valves & Controls has introduced the Pentair University customer education program for past, present and prospective clients and industry leaders in various locations throughout the world. Pentair University’s invitation-only seminars are free to attend. In some regions of the worl...

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Watson Valve Names Bob White New President

1 DAY AGO
Watson Valve Names Bob White New President

Watson Valve Services Inc. has named Robert “Bob” White as its new president. The current president, John M. Watson, will remain as the company’s CEO.

Bob has served as executive vice president, and ownership, of Watson Valve Services since its inception in 2002. He has continued to p...

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Canadian Oil & Gas Earnings Signal Industry Recovery

21 HOURS AGO

The Canadian oil and gas earnings season began yesterday with “signs of an industry recovery as Encana Corp and Precision Drilling Corp outlined plans to boost activity,” Reuters reports .

Analysts say “the uptick in optimism might be mirrored by some U.S. shale companies like Pioneer ...

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U.S. Lower 48 Sustains $150B in Cuts by Upstream Developers

1 DAY AGO

Out of the more than $370 billion in global capital expenditure cut by upstream developers across 2016 and 2017, $150 billion was slashed in the U.S. Lower 48 alone — more than three times any other single country. Largely due to responsiveness and flexibility in the unconventional space, spen...

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STEM Jobs in the U.S. Growing Faster Than Other Fields

1 DAY AGO

The U.S. Department of Commerce estimates that jobs in STEM will grow 17% by 2018—that’s 55% faster than non-STEM jobs over the next decade. Several reports have linked STEM education to the continued scientific leadership and economic growth of the U.S. However, economic projections also ...

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IMF Cuts Global Growth Forecast After Brexit Vote

3 DAYS AGO

The International Monetary Fund (IMF) cut its forecasts for global economic growth this year and next as the unexpected U.K. vote to leave the European Union creates a wave of uncertainty amid already-fragile business and consumer confidence.

The global economy is projected to expand 3.1% this year a...

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The Biopharm Industry

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This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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