According to the American Chemistry Council, the U.S. Chemical Production Regional Index dropped 3.1% in April following a 1.0% decline in March and a 0.4% decline in February. During April, chemical output fell across all regions, with the steepest decline in the Gulf Coast region. The lower level of chemical activity is directly related to supply chain disruptions and the lockdown of much of the U.S. economy during April. Production fell across all chemical segments. Within several major segments, however, production of some chemical materials increased, including supply chains tied to personal protective equipment and disinfection products.